Author

Ritesh Sharma

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Review Jul 2026

Emerging Pharmacological Therapies for Huntington's Disease: Translational Insights from Recent Clinical Trials.

Key therapeutic approaches discussed include gene-silencing technologies such as antisense oligonucleotides, RNA interference, and CRISPRCas9- based strategies, as well as small-molecule modulators targeting mutant huntingtin aggregation, proteostasis, autophagy, mitochondrial dysfunction, and neuroinflammation.

B. Semwal, Kuldeep Singh, Ritesh Sharma et al. · Current Pharmaceutical Biote... · 0 citations

#machine learning Jun 2026

When Design Rules Break: Benchmark Composition Determines Whether Label Informativeness Predicts GNN Aggregator Choice

The results suggest that benchmark composition, rather than numerical insufficiency, determines whether design rules appear to generalize, and that the Facebook-100 regime provides a concrete target for future adaptive aggregation methods.

Neha Sharma, Ritesh Sharma · arXiv.org · 0 citations