BNIP3/NIX-mediated mitophagy versus Parkin-mediated mitophagy: mechanistic differences and functional implications.
Mitophagy is a form of selective autophagy in which an isolation membrane (IM or phagophore) sequesters damaged or superfluous mitochondria for lysosomal degradation. Recent advances in receptor-mediated mitophagy, particularly the BNIP3/NIX-mediated mitophagy, have highlighted the importance of this pathway in mitocho...