Open access
Oct 2026
Clonally Expanded CD8 T Cells in AML Adopt an NK-Like Program Distinct from Canonical Exhaustion
Y. Chu, Matthew A. Cottam, C. Potts et al.
· bioRxiv · 0 citations
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Open access
Sep 2026
Somatic DDX41 mutations confer neomorphic splicing activity in the pathogenesis of myelodysplastic neoplasms
Rasika Venkataraman, N. Puccio, Tun-Yun Hsueh et al.
· bioRxiv · 0 citations
Open access
Jul 2026
Disrupting Treg lineage stability elicits RORgT-mediated plasticity and enhances anti-tumor immunity.
These findings highlight Hh/Gli2 signaling in Tregs as a mechanistic regulator of immunogenicity in the TME and a potential therapeutic target to prime tumors for enhanced responsiveness for adjuvant treatments.
Courtney A. Swain, D. Hinshaw, Ian D. Miranda et al.
· Cell Death and Disease · 0 citations