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Author

Robert Vendramelli

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Open access Nov 2026

Broad vaccine protection against globally diverse influenza A/H5Nx viruses.

Influenza A/H5Nx viruses continue to diversify and undergo gene reassortment as they infect avian and mammalian hosts worldwide. The severity of human infections varies substantially between different H5 clades and neuraminidase (NA) reassortants, creating unpredictable pandemic risk. Existing H5 vaccines, typically ba...

J. D. Del Rosario, S. Vishwanath, Simon D. W. Frost et al. · 0 citations
Open access Jul 2026

Antigen clade matching enhances protective efficacy of H5N1 DNA vaccines delivered by electroporation or lipid nanoparticles 2267127

It is demonstrated that antigenic clade-matching is likely critical for protection against H5N1 and suggest that currently stockpiled H5N1 vaccines may not protect against contemporary viruses.

E. Gary, Nicholas J. Tursi, Casey E. Hojecki et al. · 0 citations
Open access Jul 2026

Characterization of oseltamivir-resistant A(H5N1) clade 2.3.4.4b, genotype D1.1 variants identified in poultry farms of British Columbia, Canada

Despite the reduced fitness of the resistant H5N1 D1.1 variant, its emergence in the absence of viral selection pressure underscores the need for continued surveillance.

Maxime Cochin, Yacine Abed, Robert Vendramelli et al. · 0 citations

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