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Author

Roberto Chiarle

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2 papers indexed here

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Sep 2026

Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection.

TP53 mutations occur early in malignant transformation as truncal events in tumor evolution and are therefore generally present in all descendant tumor cells, creating an immunological vulnerability. Here, we examined the immunogenicity and antigenicity of p53 neoantigens emerging from these truncal mutations. Comprehe...

Koji Haratani, Bruce R. Reinhold, J. Duke-Cohan et al. · 0 citations
Review Open access Aug 2026

Targeted immunotherapies for anaplastic lymphoma kinase-positive pediatric tumors: current advances and future perspectives

Editorial on the research topic Next-Generation Treatment for Pediatric Cancer: Advancing Immunotherapy through Combinations. Cancer remains one of the leading causes of disease-related mortality among children and adolescents. Despite advances in treatments, outcomes for many pediatric tumors remain limited, particula...

Monica Maccagno, Roberta Tagliero, Roberto Chiarle et al. · 0 citations

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