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The PI3K/AKT/eNOS Signaling Axis: Molecular Mechanisms and Therapeutic Implications in Cardiovascular and Metabolic Disorders
The PI3K/AKT-eNOS signalling axis - including phosphoinositide 3- kinase (PI3K)/protein kinase B (AKT)-endothelial nitric oxide synthase (eNOS) - is a crucial molecular pathway that governs vascular tone, blood circulation, glucose metabolism, and cellular survival, thereby upholding cardiovascular and metabolic ho...