Open access
Sep 2026
Biocatalytic Synthesis of Diethyl Succinate in Hydrophobic Trioctylphosphine Oxide (TOPO)-Based Reactive DES
Diethyl succinate (DEtS) synthesis by lipase-catalyzed direct esterification was successfully carried out in succinic acid (SA):trioctylphosphine oxide (TOPO) mixtures acting as reactive deep eutectic solvents (rDES). By this strategy, the succinic acid concentration in this non-aqueous eutectic mixture reaches up to 1...
Susana Nieto, Francisco J. Ruiz, J. Martinez-Garcia et al.
· Molecules · 0 citations