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R. Fleming

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Preprint Oct 2026

gpuGEM: GPU-based linear optimisation of genome-scale metabolic models

Summary: Genome-scale metabolic models increasingly challenge CPU linear-programming solvers in repeated optimisation. We present gpuGEM, an open-source Python library for GPU-based optimisation using NVIDIA cuOpt, with size-adaptive settings validated against HiGHS and Gurobi. Across ten models spanning four orders of...

Farid Zare, T. Hulshof, I. Thiele et al. · 0 citations
Preprint Sep 2026

kgsteward: a tool for building, reproducing and maintaining distributed knowledge graphs

Collaborative research projects in life sciences increasingly need to integrate private, embargoed consortium data with public reference databases in order to reach statistically meaningful interpretations. The Resource Description Framework (RDF) is well suited to this task: it facilitates the integration of heterogen...

Marco Pagni, Robin Engler, Frédéric Burdet et al. · 0 citations

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