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Author

Rong Cao

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Sep 2026

A Novel Alkaline-Stable Chitin Deacetylase from Chitiniphilus eburneus for Eco-Friendly Preparation of Specific Deacetylated Products

Chitin deacetylase is the key enzyme responsible for the biological deacetylation of chitin. However, its limited sources and low catalytic efficiency toward α-chitin present significant barriers to the bioproduction of chitosan. Herein, a chitin deacetylase Ce1425 sourced from Chitiniphilus eburneus was identified,...

Yuan Yu, Kai-Liang Leng, Rong Cao et al. · 0 citations
Jul 2026

Bidirectional Loop Engineering Uncovers a Structural Determinant for Product Specificity in GH46 Family Chitosanases.

A bidirectional loop-engineering strategy is employed to decipher the function of a conserved loop (XDXXP) in GH46 chitosanases and reveals that the loop modulates the geometry, electrostatics, and hydrophilicity of the substrate-binding cleft, thereby influencing substrate recognition and product specificity.

Mao-Yue Li, Minjuan Gui, Yingying Wei et al. · 0 citations

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