Open access
Sep 2026
Directed biosynthesis of the designer peptidyl nucleoside antibiotics featuring a simplified azetidine-containing moiety
Fungal and fungal-like pathogen infections pose escalating threats to the global one-health, thus underscoring the urgent need to reverse this trend by accelerating the development of novel antifungal drugs. Polyoxin (POL), a group of structurally related nucleoside antibiotics, is an eco-friendly fungicide targeting f...
Rong Gong, Tianzhu Li, Li-Wei Zhou et al.
· Synthetic and Systems Biotec... · 0 citations