Guchang capsule alleviates inflammatory bowel disease by downregulating lncRNA THRIL and inhibiting the p38 MAPK/NF-κB signaling pathway.
BACKGROUND Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with limited treatment options. Guchang capsule (GC) has been used in traditional Chinese medicine, but its effects on IBD and the underlying molecular mechanisms remain unclear. METHODS A dextran sulfate sodium (DSS)-induced colitis model...