Open access
Jul 2026
Macrophage NPM1 drives anti-tumor immunity via the STAT3-CCRL2 axis
Background Although nucleophosmin (NPM1) is a well-characterized oncogene in acute myeloid leukemia, much less is known about its role in solid tumor immunity. Here, we examined the function of NPM1 in regulating anti-tumor immunity within the tumor microenvironment. Methods The proportion and functional changes of mac...
Lei Hong, Yue Yang, Yuwen Han et al.
· Frontiers in Immunology · 0 citations