Author

Ru Qiu

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Open access Sep 2026

N-acetyltransferase 10 promotes glioblastoma radioresistance by suppressing immunogenic ferroptosis through N4-acetylcytidine of SLC7A11 mRNA

Radiotherapy is the standard treatment for glioblastoma (GBM), but its efficacy is severely compromised by radioresistance. While aberrant RNA modifications contribute to radioresistance, specific epitranscriptomic vulnerabilities remain underexplored. We integrated quantitative proteomics, N 4 -acety...

Shu-Shu Hu, Jin-Mei Cheng, Yuan Liu et al. · Journal of Experimental &amp... · 0 citations

Open access Aug 2026

A confound-diagnostic toolkit for in silico perturbation with single-cell foundation models

A reusable confound-diagnostic framework is developed that applies matched controls to test whether native perturbation readouts contain information beyond these confounds and warrant biological interpretation, and helps determine when foundation-model perturbation readouts warrant biological interpretation.

Ru Qiu, Max Mingqian Zhao · bioRxiv · 0 citations