Ruchitha Korem

B-068 Functional inhibition of target YB1 via rationally designed ligand library for mechanistic biomarker validation in triple negative breast cancer models

Breast cancer is one of the leading causes of death worldwide. Triple negative breast cancer accounts for 10-15% of all the breast cancer cases, and it is the most aggressive form. YB1 is a multifunctional protein that plays a major role in tumor progression, drug resistance, and metastasis in multiple cancers. Y...