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Ruijie Quan

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Preprint Oct 2026

Beyond the Transcriptome: Chromatin-Informed Prediction of Cell-State-Dependent Perturbation Responses

Predicting transcriptional responses to genetic perturbations is central to understanding gene function. Existing predictors primarily rely on transcriptomic measurements, although chromatin accessibility provides complementary information about the cellular context in which perturbations act. Using this information re...

Jia-Fa Ruan, Chen-Yan He, Rui-Jie Quan et al. · 0 citations
#artificial intelligence Preprint Sep 2026

PDE-JEPA: Predictive Representation Learning of Latent Dynamics Modeling for Parametric PDEs

Physical trajectories contain more than snapshots of a system: they also reveal how its states evolve under governing conditions. However, representation learning for parametric partial differential equations (PDEs) has largely relied on reconstruction-based objectives that emphasize recovering observed physical fields...

Zhen-Tao Tan, Jian-Rong Zhang, Rui-Jie Quan et al. · 0 citations
Preprint Aug 2026

From Points to Edges: Edge-Conditioned Spectral Operators for Physics-Sensitive PDE Learning

Neural operators have become a central tool for solving partial differential equations (PDEs), with spectral operators offering efficient global mixing across spatial locations. However, many PDEs contain physics-sensitive local structures that are critical to the underlying physical behavior. For example, in Darcy flo...

Zhen-Tao Tan, Rui-Jie Quan, Yi Yang · 0 citations
Preprint Aug 2026

LayerRecall: A State-Conditioned Memory Router for Long-Horizon Consistency in Video Generation

Autoregressive video diffusion enables scalable long-video generation by producing chunks from a bounded recent context. While recency-based caching preserves local continuity, it evicts historical cues needed when subjects, objects, scenes, or attributes reappear. Existing memory mechanisms expose models to nonlocal h...

Yixuan Ding, Jia-Hao Kong, Wei Huang et al. · 2 citations · ⚡2
Preprint Aug 2026

Beyond Pixels: From Video Priors to 4D Worlds

Direct latent-to-4D generation is introduced and instantiate it as Latent-to-4D, which bypasses RGB by aligning a video latent with the token grid of a pretrained 4D decoder and refining it through frame-wise and global spatiotemporal attention.

Zihao Liu, Xi Shen, Zhen Zhou et al. · 0 citations

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