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Open access Oct 2026

Angiogenesis-RNA modification in diabetic retinopathy: biomarkers and targets.

AIM To identify biomarkers and potential therapeutic targets related to angiogenesis and RNA modification in diabetic retinopathy (DR). METHODS The Gene Expression Omnibus (GEO) datasets GSE12610, GSE87433, and GSE111465, which contain retinal samples from diabetic and normal mice, were analyzed to identify different...

Xue Wang, Dan-Ping Wu, Wei Du et al. · 0 citations
Open access Sep 2026

HERC4-mediated ubiquitination licenses RIPK1 to initiate TNF-induced cell death.

TNF can activate both prosurvival and prodeath signaling downstream of tumor necrosis factor receptor 1 (TNFR1). Survival signaling originates from TNFR1-containing membrane-bound complex I, while death signaling is driven by cytosolic complex II. Receptor-interacting protein kinase 1 (RIPK1) is a central component of...

Hao-Hao Lu, Tong-De Du, Lin Li et al. · 0 citations

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