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Author

Rui Li

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Review Sep 2026

The emerging landscape of polymerase θ in tumor pathogenesis and precision treatment.

A comprehensive and updated synthesis of Polθ's structural architecture, regulatory networks, and context-dependent functions across major malignancies, including ovarian, breast, lung, and colorectal cancers, and a critical evaluation of current Polθ inhibitors.

Ming-Dian Lei, Yuxuan Li, Zhi-Peng Xie et al. · 0 citations

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