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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Rui Li

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2 papers indexed here

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Review Sep 2026

The emerging landscape of polymerase θ in tumor pathogenesis and precision treatment.

DNA polymerase θ (Polθ) has emerged as a central yet paradoxical regulator of genome stability and tumor progression. Unlike conventional DNA repair factors, Polθ governs an error-prone double-strand break repair pathway-termed theta-mediated end joining (TMEJ)-which becomes essential for survival in homologous recombi...

Ming-Dian Lei, Yuxuan Li, Zhi-Peng Xie et al. · 0 citations
Open access Sep 2026

MED24 deficiency promotes R-loop accumulation and sensitizes to SN-38 in triple-negative breast cancer

The application of DNA topoisomerase I (TOP1) inhibitors in triple-negative breast cancer (TNBC) still needs to be optimized. The principle of synthetic lethality represents a promising strategy to optimize TNBC treatment using SN-38, a representative TOP1 inhibitor and the active metabolite of irinotecan. MED24, yet...

Tao Shen, Xin-Hua Liu, Pei Huang et al. · 0 citations

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