Open access
Jul 2026
LMAN2 promotes breast cancer progression and deduces cell sensitivity to doxorubicin through stearoyl-CoA desaturase.
BACKGROUND Dysregulated lipid metabolism and chemoresistance are key drivers of breast cancer progression. Lectin, mannose-binding 2 (LMAN2) is frequently overexpressed in human breast tumors and functions as an oncogenic driver. However, whether LMAN2 contributes to chemoresistance remains unknown. METHODS We integr...
Changjiao Yan, Fengqiang Cui, Chutuo Liu et al.
· Breast Cancer Research · 0 citations