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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Rui Liu

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2 papers indexed here

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Open access Sep 2026

PTTG1-driven self-amplifying loop with SP1 and ENO1 promotes IRF4-mediated myeloma progression and bone destruction

Multiple myeloma (MM) is a neoplastic disorder of plasma cells within the hematopoietic system and is characterized by osteolytic lesions. Despite significant advances, the molecular underpinnings of myeloma and its associated bone pathologies remain elusive, and there is an unmet need for effective targeted therap...

Rui Liu, Ya-Zhu Huang, Zhi-Hong Fang et al. · 0 citations
Open access Aug 2026

SEI1 complex silences p53 to drive myeloma progression

Summary SEI1 is overexpressed in multiple myeloma and correlates with poor prognosis. In this study, we identify SEI1 as a crucial driver of myeloma pathogenesis through a previously unrecognized mechanism: transcriptional inactivation of the tumor suppressor p53. Mechanistically, SEI1 forms a transcriptional complex w...

Rui Chen, Rui Liu, Zhi-Hong Fang et al. · 0 citations

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