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Oct 2026

Lycium barbarum polysaccharides and melatonin alleviate cadmium-induced hepatic metabolic injury associated with alterations in PI3K/AKT signaling.

Lycium barbarum polysaccharides (LBP), bioactive macromolecules derived from Lycium barbarum, exhibit metabolic regulatory and hepatoprotective activities. Cadmium (Cd) exposure is a major environmental concern associated with hepatic metabolic dysfunction and liver injury; however, the potential protective role of LBP...

Geng-Sheng Yu, De-Hui Zhou, Ze-Hao Wang et al. · 0 citations
Open access Oct 2026

Lycium barbarum polysaccharides alleviate cadmium-induced renal injury in ducks by activating the Nrf2-mediated antioxidant defense pathway

It is found that Cd promoted lipid accumulation, disrupted lipid metabolism, and thereby induced renal immunosuppression, and LBP effectively alleviated Cd-induced renal injury, suggesting beneficial effects against Cd-triggered nephrotoxicity.

Xue-Ru Wang, Dong-Di Liu, Yong-Gang Ma et al. · 0 citations
Nov 2026

Co-exposure to deoxynivalenol and hexavalent chromium is associated with intestinal injury, dysbiosis, and activation of ferroptosis and pyroptosis related pathways in broilers.

The combined pollution of deoxynivalenol (DON) and hexavalent chromium [Cr(VI)] during crop and food processing poses a serious threat to the intestinal health of poultry and humans. However, the specific regulatory mechanisms underlying intestinal toxicity induced by DON and Cr(VI) co-exposure in broilers remain uncle...

Yue-Ming Gu, Xin-Yuan Miao, Lin-Rui Fan et al. · 0 citations
Open access Jul 2026

Xuebijing alleviates acute hydrogen sulfide-induced pyroptosis in rat spleen via suppression of the caspase-1/NLRP3 pathway

It is demonstrated that H2S induces splenic pyroptosis via the NF-κB/NLRP3/caspase-1 pathway, and that XBJ confers protection by interrupting this cascade, offering a mechanism-based candidate for the treatment of acute H2S poisoning.

Lulu Ding, Yuhao Han, Yan Chen et al. · 0 citations

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