Noni fruit phenolic-rich extract ameliorated non-alcoholic fatty liver disease through regulating gut microbiota and bile acids profiling by targeting FXR-FGF15 signaling.
BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease globally, covering a spectrum from simple hepatic steatosis to steatohepatitis. With limited pharmacological interventions available, there is growing interest in natural products for NAFLD prevention and management. The...