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Author

Rui Pan

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Review Open access Jul 2026

Bone niche-driven antitumor immune failure in osteosarcoma: Mechanisms and therapeutic implications (Review)

An evidence-graded bone niche-driven framework of layered antitumor immune failure in OS is presented, in which the skeletal niche is not treated as a passive anatomical background but as a spatial and temporal organizer of immune-cell trafficking, myeloid remodeling, treatment-induced repair programs, systemic niche c...

Bolin Tang, Yu-Huai Wu, Jian-Ping Liu et al. · 0 citations

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