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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ruirui Shi

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2 papers indexed here

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Review Sep 2026

A Unified Mechanistic Framework for Copper Toxicity in Neutrophils: Metabolic Rewiring, Cell-Death Crosstalk, and Immune Dysfunction.

SIGNIFICANCE Copper is an essential redox-active micronutrient, but failure of copper compartmentalization can convert it from a catalytic cofactor into a source of oxidative, proteotoxic, and mitochondrial stress. Neutrophils are a plausible target of this transition because their antimicrobial functions depend on tig...

Rui-Rui Shi, Si-Yue Chen, Ting-Ting Chen et al. · 0 citations
Open access Jul 2026

ETV6 Rearrangement Suppresses CDKN1B Transcription by Disrupting an Intragenic Super-Enhancer in Acute Lymphoblastic Leukemia.

It is demonstrated that ETV6 functions as a regulatory element via ETV6-SE in ALL, with CDKN1B as a key target and CRISPR interference and knockout experiments revealed the core enhancer region within ETV6-SE responsible for CDKN1B regulation.

Wenqian Xu, Xiaofang Ma, Xue Sun et al. · 0 citations

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