Author

Rui Zhao

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Open access Oct 2026

Agrin‐Enriched Neonatal Spinal Cord‐Derived Extracellular Vesicles Bypass Age Barriers to Organize Spinal Cord Repair

ABSTRACT Spinal cord injury (SCI) poses a formidable challenge in regenerative medicine, with current therapeutic strategies proving largely unsuccessful in achieving functional repair. Notably, paediatric patients and neonatal mice exhibit spontaneous and efficient regeneration after SCI, while the mechanisms remain e...

Yong-Feng Zhang, Qi Liu, Bei-Bei Yu et al. · Journal of Extracellular Ves... · 0 citations

Open access Oct 2026

Drp1 in M1 layer V GABAergic neurons orchestrates rTMS-mediated motor restoration and analgesia after spinal cord injury

Spinal cord injury (SCI) leads to chronic motor and sensory deficits, with progressive secondary neurodegeneration posing a major therapeutic challenge. Although high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) over the primary motor cortex (M1) shows therapeutic potential, its underlying cellular...

Xiao-Long Sun, Rui Zhao, Kun-Long Zhang et al. · Experimental and Molecular M... · 0 citations

Open access Sep 2026

Single-Nucleus Transcriptomic Mapping Reveals Correlative Microglial Changes Associated with rTMS in the Motor Cortex After Spinal Cord Injury

The snRNA-seq analysis identifies M1 cortical microglial transcriptional and communication changes that correlate with SCI-induced NP and provides a hypothesis-generating preclinical foundation for future mechanistic studies targeting cortical microglia with rTMS.

Kun-Long Zhang, Xin-Jiang Yang, Rui-Bin Hou et al. · Journal of Inflammation Rese... · 0 citations