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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Ruilan Mo

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Open access Aug 2026

Berberine induces PD-L1 degradation via the autophagy-lysosome pathway through the PI3K-Akt pathway and enhances immunogenic cell death in triple-negative breast cancer

Objective This study aimed to investigate the regulatory effect and molecular mechanism of Berberine (BBR) on programmed death-ligand 1 (PD-L1) expression in Triple-Negative Breast Cancer (TNBC) cells. Methods In vitro cellular experiments (using MDA-MB-231 and BT-549 cell lines) and mouse models (Balb/c-nu and Balb/c...

Yuqin Wei, Qiudan Huang, Xin Wei et al. · 0 citations

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