Single-cell transcriptomic analysis reveals that Trametes robiniophila Murr. (Huaier) granules protect against ulcerative colitis by targeting macrophage-associated cGAS-STING signaling.
ETHNOPHARMACOLOGICAL RELEVANCE Trametes robiniophila Murr. (Huaier granules) is a medicinal fungus with over 1,600 years of historical use in traditional Chinese medicine. It has been traditionally applied to alleviate "intestinal wind" with bleeding, dysentery, and other inflammatory gastrointestinal disorders, in add...