Inhibition of ALPK1 attenuates myocardial ischemia-reperfusion injury in Nur77-deficient mice via suppressing XPO1-dependent pathway.
Despite being the initial intervention of choice, revascularization for myocardial ischemia-reperfusion (I/R) injury remains constrained, making the exploration of novel therapeutic targets imperative. Alpha-kinase 1 (ALPK1) knockdown mitigates ischemic brain injury, whereas its function in cardiac I/R injury requires...