Open access
Aug 2026
Rapamycin‐nanoliposomes target the mTORC1‐mediated autophagy–lysosomal and NLRP3/Caspase‐1 pathways to inhibit nucleus pulposus cell senescence in intervertebral discs
Collectively, rapa‐lipos target mTORC1‐mediated NCP and ALP to inhibit NP cell senescence, offering a promising strategy for intervertebral disc degeneration prevention.
Hui Xing, Miao Yu, Jia-Bin Liu et al.
· Bioengineering & Translation... · 0 citations