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Author

Ruo-Jun Zong

2 papers indexed here

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Open access Sep 2026

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

ABSTRACT Congenital hypothyroidism (CH) is a prevalent endocrine disorder associated with cerebral hypogyrification in neonates and young children, yet the vulnerable cell types and underlying molecular mechanisms remain elusive. Using a gyrencephalic CH pig model, we observed cerebral atrophy and cortical hypogyrifica...

Ying Zhang, Xiao Wang, Hong-Yan Ma et al. · 0 citations
Open access Aug 2026

TFEB Deficiency Impairs Male Fertility Through Mitochondrial Dysfunction.

Transcription Factor EB (TFEB) is widely recognized as a key transcription factor regulating lysosomal biogenesis and autophagy. Although the TFEB gene is highly expressed in the testes, the mechanism by which it affects male fertility remains unclear. Here, we report that spermatogonia-specific deletion of TFEB in mic...

Hong-Xia Li, Guo-Qing Zhao, Ruo-Jun Zong et al. · 0 citations

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