Author

Ruo-Xuan Liu

2 papers indexed here

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Open access Aug 2026

Tafolecimab mitigates ox-LDL-induced macrophage foam cell formation and inflammation by modulating SR-A/ABCG1 expression and inhibiting the NF-κB/MAPK pathways

Macrophage foam-cell formation, triggered by excessive uptake of oxidized low-density lipoprotein (ox-LDL) and subsequent intracellular lipid accumulation, represents a critical pathological event in atherosclerotic plaque initiation that drives localized inflammatory responses. The present study investigated the effec...

Xin-Yi Yu, Xiao-Dan Liu, Yu-zhen Dang et al. · Biomedical Reports · 0 citations

Open access Sep 2026

Beauvericin exhibits antitumor activity in pancreatic cancer cells: Integrative analysis suggests potential modulation of the KEAP1-NRF2-HMOX1 axis and survival signaling pathways

To investigate the anticancer effects of Beauvericin (BEA) and elucidate its potential mechanisms in pancreatic cancer cells, a malignancy characterized by marked heterogeneity and frequent chemoresistance. The effects of BEA on the proliferation, migration and apoptosis of Mia PaCa-2 cells were evaluated via CCK-8,...

Xin-Yi Yu, Xiao-Dan Liu, Jie Ouyang et al. · Scientific Reports · 0 citations