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Author

Rusiou Hsu

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Open access Sep 2026

Targeting prostaglandin catabolism via topical nanotherapy rescues vision in ischemic optic neuropathy

Ischemic optic neuropathy is a leading cause of acute vision loss and currently lacks effective therapy. Here, we identify 15-hydroxyprostaglandin dehydrogenase (15-PGDH), the key enzyme responsible for prostaglandin degradation, as a metabolic checkpoint in ischemic optic neurodegeneration. Analysis of human ischemic...

Shweta Modgil, Rusiou Hsu, M. Shariati et al. · 0 citations

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