Mitral Annular Calcification as a Marker of the HFpEF Phenotype: The Interplay of Cardiac Remodeling, Age, and Sex.
Mitral annular calcification (MAC) is recognized as a marker of cardiovascular risk. However, the structural and hemodynamic predictors of its presence and severity remain insufficiently defined. We analyzed a large, consecutive cohort of 49,093 individuals undergoing echocardiography at our tertiary medical center, cl...