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Author

Ruting Wang

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Open access Aug 2026

Risk and mechanisms of artificial sweetener-induced metabolic dysfunction-associated steatotic liver disease: Insights from multi-level bioinformatics and in vitro assays.

The association between artificial sweeteners (ASs), which are widely used sugar substitutes, and metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear. In this study, we employed an integrated approach to investigate the potential risk and mechanisms of AS-induced MASLD. Using network toxico...

Ruting Wang, Hongxi Wu, Jia-Le Liang et al. · 0 citations
Aug 2026

Hypoxia-activated endothelial cells drive stemness and vasculogenic mimicry in NSCLC via a HIF-1α/ITPR3 axis.

Hypoxia-activated endothelial cells drive NSCLC aggressiveness and VM through a paracrine axis involving ITPR3-mediated ER calcium activation, and this HIF-1α/ITPR3 axis represents a potential therapeutic target for disrupting the tumor-vascular niche in NSCLC.

Wen-Hao Ji, Shi-Zhou Yang, Xiao-Jing Lai et al. · 0 citations

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