Author

Ryohei Ogawa

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Open access Aug 2026

4,4'-dimethoxychalcone induces thermosensitive impairment of SIRT3-associated mitochondrial signaling and apoptotic cell death with therapeutic potential in cancer.

DMC is identified as a thermosensitive inhibitor of SIRT3 and mechanistic insights into its potential to disrupt mitochondrial homeostasis for targeted cancer therapy are provided.

Yu Song, Qing-Li Zhao, Ryohei Ogawa et al. · Chemico-Biological Interacti... · 0 citations