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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Ryosuke Takahashi

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Open access Oct 2026

Tegmental atrophy in isolated REM sleep behaviour disorder: ex vivo MRI–informed in vivo imaging

Isolated rapid eye movement (REM) sleep behaviour disorder (iRBD) is an early-stage synucleinopathy characterized by brainstem pathology. In rodents, the pontine tegmentum contains a REM sleep centre, the sublaterodorsal nucleus, which expresses corticotropin-releasing hormone binding protein (CRHBP). While the invol...

Masakazu Hirose, Kenji Yoshinaga, Yoshifumi Mori et al. · 0 citations

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