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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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S. Aghamohammadzadeh

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Open access Sep 2026

A brain-penetrant TRPML1 agonist enhances autophagy–lysosomal function and mitigates pathology in aged models of Parkinson’s and Alzheimer’s diseases

Age-related decline in autophagy–lysosomal pathway function is a key contributor to the accumulation of toxic protein aggregates, neuroinflammation, and neuronal loss in neurodegenerative diseases. Transient receptor potential mucolipin-1 (TRPML1) is a lysosomal Ca²⁺ channel that coordinates acute lysosomal signaling...

V. Cullen, Jun-Sheng Yang, Xiang-Yang Yu et al. · 0 citations

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