Retinal nerve fiber layer and ganglion cell layer thinning as biomarkers of cognitive decline in multiple sclerosis: an 18-month prospective cohort study.
BACKGROUND Retinal neurodegeneration measured by optical coherence tomography (OCT) has emerged as a candidate biomarker of central nervous system (CNS) damage in multiple sclerosis (MS). However, its relationship with cognitive dysfunction - a clinically relevant and underappreciated dimension of disease burden - rema...