It is demonstrated that the 14-3-3eta protein detects a clinically meaningful proportion of patients who lack conventional autoantibodies, capturing nearly one-third of individuals who are anti-CCP-negative or RF-negative, and 1 in 5 among those negative for both markers, thereby underscoring its complementary role in...
A. Marotta, S. Bleakley, Y. Gui· Clinical Chemistry· 0 citations
Axial Spondyloarthritis (axSpA) is a chronic autoimmune disease often resulting in spinal fusion and significant disability if left untreated. A major challenge in early intervention is the prolonged diagnostic delay, typically 7-10 years, driven by symptom overlap with chronic lower backpain and frequent misdiag...
A. Marotta, S. Bleakley, Y. Gui et al.· Clinical Chemistry· 0 citations
This study examines the discriminative performance of anti-14-3-3eta AAbs in patients with axSpA, including those with radiographic and non-radiographic-axSpA from MBP, and its discrimination improves when age, sex, CRP, and HLA-B27 are added.
A. Marotta, C. Cavill, S. Bleakley et al.· Clinical Chemistry· 0 citations
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