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Review Oct 2026

NON-OPIOID SURGICAL PAIN BLOCKER FOR LUMBAR SPINE FIXATION SURGERY: RATIONALE AND DESIGN OF AN ADAPTIVE PHASE II/III CLINICAL TRIAL (STX-103)

Acute postsurgical pain following lumbar spine fixation surgery remains inadequately managed by current opioid-based regimens, resulting in delayed mobilization, prolonged hospital stays, worse recovery, and an increased risk for chronic postoperative pain (CPSP) and opioid use disorder (OUD). Local anesthetics suc...

HR Jonkman, F. V. Van Tol, S. Bruins et al. · 0 citations

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