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S. Bufarwa

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Open access 2026

Profiling phenolic constituents and tissue-specific biological activities of the edible mushroom Pleurotus ostreatus: Evidence from in vitro and in silico studies

Both extracts showed antimicrobial activity and selective cytotoxicity against HepG2 cells, with minimal toxicity toward normal WI-38 fibroblasts, and stable interactions of major phenolics with the Bcl-2 protein were confirmed, confirming the importance of tissue-specific evaluation of mushroom extracts.

Salma O. Jadallah, Yassmin F. El Greeby, Mohammed Alakib et al. · 0 citations
Aug 2026

Integrated In Silico Profiling of Altissimacoumarin H in Prostate Cancer-Related Molecular Networks

This study investigated Altissimacoumarin H (ATSC), a naturally occurring terpenylated coumarin, using an integrated in silico workflow combining target prediction, network pharmacology, transcriptomic assessment, molecular docking, molecular dynamics, ADME/toxicity prediction, and density functional theory (DFT).

S. Bufarwa, M. Belaidi · 0 citations

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