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Author

S. Chan

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Open access Sep 2026

Effect of liver function on clinical outcomes in patients with unresectable hepatocellular carcinoma treated with first-line atezolizumab-bevacizumab: an Asia-Pacific multicenter retrospective analysis.

INTRODUCTION AND OBJECTIVES Atezolizumab+bevacizumab (atezo-bev) is the standard first-line therapy for unresectable hepatocellular carcinoma (uHCC), but pivotal trials were limited to patients with preserved liver function. Therefore, this study aims to evaluate the prognostic effect of Child-Pugh (CP) class and Album...

Yeokyeong Shin, Young Jae Kim, D. Tai et al. · 0 citations
Review Open access Sep 2026

RAS-targeted therapies for pancreatic cancer

Pancreatic adenocarcinoma (PDAC) is a RAS-driven cancer with poor prognosis. Although tremendous progress has been made in other cancers with the development of targeted therapies and immunotherapy, cytotoxic chemotherapy remains the mainstay of treatment for PDAC. For decades, the therapeutic development of RAS-target...

L. Chan, Thomas G. Kwong, Johnny C. W. Yau et al. · 0 citations

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