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Author

S. Chirumbolo

2 papers indexed here

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Review Open access Sep 2026

Melatonin beyond chronobiology: integrating pharmacokinetics, dose-exposure forecasting, and clinical evidence

Melatonin is established as a regulator of circadian timing and sleep, while a wider range of receptor-dependent and receptor-independent biological effects has generated interest in additional therapeutic applications. This review critically examines whether those proposed effects can be interpreted within an exposure...

S. Pandolfi, F. Paone, Marco Metalla et al. · 0 citations
Aug 2026

A Dynamical Systems Evaluation of the Hypothesis That Genetic Codes Define Domains of Life.

The recent hypothesis that domains of life are identified by their genetic codes proposes a direct correspondence between genetic-code stabilization, progenote-to-cell transitions, and the emergence of biological domains. Although conceptually appealing, this framework assumes that genetic-code divergence is the primar...

S. Chirumbolo · 0 citations

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