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S. Cochrane

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Open access Aug 2026

Daily HIV pre-exposure prophylaxis enhances monocyte activation and reprogrammes immune cell metabolism

Introduction Pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine (TDF/FTC) is highly effective for HIV prevention. While antiretroviral therapy (ART) is linked to chronic inflammation in people living with HIV, its direct effects on immune phenotype, function, and metabolism in HIV-negative individuals remain...

G. Jameson, D. Murphy, Isabella Batten et al. · 0 citations

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