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Jun 2026

Mutations in the three synapsin genes lead to profound social deficits and cortical dysfunctions.

Results show that synapsin deletion is associated with a distinct profile of social and repetitive behavioral abnormalities, accompanied by a region-selective alteration in IL-mPFC firing activity, which indicates a marked deficit in sociability and social recognition in TKO mice.

Noemi Nicosia, Elena Monzani, Maria Regoni et al. · 0 citations