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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

S. Dass

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2 papers indexed here

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Review Open access Sep 2026

First-line biologic and targeted synthetic DMARDs versus methotrexate in early rheumatoid arthritis: a meta-analysis of remission outcomes.

OBJECTIVES To evaluate initial therapy with biologic and targeted synthetic DMARDs (b/tsDMARDs), compared with methotrexate, in patients with early RA. METHODS We systematically reviewed and meta-analysed randomised-controlled trials comparing initial b/tsDMARDs, combined with methotrexate or as monotherapy, against...

M. Russell, Chun-Kong Chan, Aran Sasitharan et al. · 0 citations
Open access Aug 2026

High-sensitivity flow cytometry in rheumatoid arthritis shows that early B-cell subset depletion is linked to 5-year rituximab response, while failure to deplete B cells occurs early in subsequent poly-refractory disease.

OBJECTIVES To assess complete depletion of B-cell subsets using high-sensitivity flow cytometry (HSFC) across the therapeutic spectrum of rheumatoid arthritis (RA): from good initial rituximab (RTX) responders to poly-refractory RA (failed all biologic or targeted synthetic disease-modifying antirheumatic drug classes)...

A. Tonutti, K. Abacar, Paula David et al. · 0 citations

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