Author

S. De Smedt

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Open access Oct 2026

Alpha-galactosylceramide as mRNA vaccine adjuvant modulates cellular immunity against tuberculosis and contributes to antigen-specific lung-associated T cells with a TRM-associated phenotype following prime-pull strategy

Tuberculosis (TB) remains the leading cause of death from a single infectious agent worldwide, highlighting the need for improved vaccines beyond the limited protection currently provided by the Bacillus Calmette-Guérin (BCG) vaccine. Here we investigated the immunological impact of incorporating alpha-Galactosylcera...

Ilke Aernout, Thomas Ehouarne, Kevin Mwangi et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

Detaching Photosensitive Nanoparticles from Cells Prevents Them from Remaining in Cells after Photoporation

ABSTRACT Efficient and safe intracellular delivery of macromolecules, like nucleic acids, remains a major challenge in ex vivo cell engineering. While photoporation is a highly attractive method for cytosolic delivery of (macro)molecules, photosensitizers remaining in the photoporated cells may pose safety concerns, es...

Tao Lu, Mina Nikolić, Bai-Hao Huang et al. · Advancement of science · 0 citations