Author

S. Faust

2 papers indexed here

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Sep 2026

The platform trial in COVID-19 priming and BOOsting (PICOBOO): The reactogenicity of nine licensed COVID-19 vaccines delivered in immunocompetent adults.

BACKGROUND PICOBOO is a randomised, Bayesian adaptive trial evaluating immunogenicity and reactogenicity of licensed COVID-19 vaccines in immunocompetent individuals aged >12 years. We present reactogenicity data for nine vaccines administered as additional doses within adult strata based on age cohort and primary vacc...

McLeod C, M. Dymock, K. Flanagan et al. · Vaccine · 0 citations

Open access Oct 2026

Immunogenicity and safety of BPZE1, an intranasal live attenuated pertussis vaccine, evaluated with and without tetanus-reduced diphtheria-acellular pertussis vaccine in healthy children aged 6-17 years: a randomised, active-controlled and placebo-controlled, phase 2b trial.

BACKGROUND Pertussis remains an important public health issue, in part because current vaccines fail to induce potent mucosal immunity against the causative agent, Bordetella pertussis. In contrast, the live attenuated vaccine BPZE1 induces robust nasal secretory IgA (S-IgA) and protects against B pertussis infection i...

S. Faust, J. Céspedes, L. Avila et al. · Lancet. Infectious Diseases... · 0 citations