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Open access Sep 2026

Extracellular Vesicles From Heat‐ and Oxidative‐Stressed Granulosa Cells Improve Redox Balance and Embryo Development in Bovine Oocytes

ABSTRACT In vitro culture (IVC) exposes oocytes to suboptimal conditions that may disrupt redox homeostasis and compromise developmental competence. Extracellular vesicles (EVs) mediate intercellular communication, and their cargo reflects the physiological state of donor cells. We hypothesized that EVs derived from he...

Judith Diaz-Muñoz, Y. Cajas, K. Cañón-Beltrán et al. · 0 citations
Aug 2026

A fast and simple one-step oocyte vitrification and warming protocol: proof-of-concept validation in the mouse model.

Oocyte vitrification is widely used in fertility preservation and assisted reproductive technologies (ART), but current protocols rely on sequential cryoprotectant exposure steps that are labor-intensive and operator-dependent. This study evaluated the feasibility of a simplified one-step vitrification and warming prot...

F. Inoue, M. Acacio, E. Mestres et al. · 0 citations

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