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S. Ghosh

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Aug 2026

Therapeutic targeting of ROCK reverses EMT in lung cancer cells by impeding TAZ in Hippo signalling pathway.

The therapeutic potency of Lomitapide was established to target Hippo pathway through disrupting ROCK activity in EMT dynamics, evident by upregulation of epithelial markers and downregulation of mesenchymal markers, through western blotting, qRT-PCR and immunofluorescence studies.

Basab Ghosh, S. Ghosh · 0 citations