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Author

S. Ghosh

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Oct 2026

AIEgen-Based Dual-Functional Platform for Cancer Cell Imaging and Photodynamic Therapy

A new paradigm shift in translational healthcare research focuses on the development of a minimally invasive image-guided therapeutic strategy. The current study presents the design and synthesis of a series of donor–acceptor (D–A)-type aggregation-induced emission luminogens (AIEgens) specifically engineered for roo...

Hirakjyoti Roy, Debika Barman, Ratul Chakraborty et al. · 0 citations
Aug 2026

Sustainably Synthesized Small Molecule Therapeutic Aggregates Attenuate Aβ-Induced ROS-Mitochondrial-Apoptotic Cascade in Alzheimer's Disease.

Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) aggregation, oxidative stress, mitochondrial dysfunction, and progressive neuronal loss, yet effective disease-modifying therapeutics remain limited. Herein, we report the sustainable synthesis of two triphenylamine-based donor-acceptor (D-A) scaffolds, TPA-IM...

Priyam Ghosh, Sayantani Mukhopadhyay, Srinivas Rati et al. · 0 citations
Aug 2026

Therapeutic targeting of ROCK reverses EMT in lung cancer cells by impeding TAZ in Hippo signalling pathway.

The therapeutic potency of Lomitapide was established to target Hippo pathway through disrupting ROCK activity in EMT dynamics, evident by upregulation of epithelial markers and downregulation of mesenchymal markers, through western blotting, qRT-PCR and immunofluorescence studies.

Basab Ghosh, S. Ghosh · 0 citations

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