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Author

S. Granica

2 papers indexed here

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Open access Aug 2026

From gut-derived metabolites to topical targets: 5-(3',4'-dihydroxyphenyl)-γ-valerolactone as an anti-inflammatory candidate for skin and mucosal inflammation.

Plant-derived compounds can be transformed by the human gut microbiota into postbiotic metabolites with distinct structures and biological activities, providing insight into the mechanisms underlying the pharmacological effects of medicinal plants. Among them, 5-(3',4'-dihydroxyphenyl)-γ-valerolactone (DHPV), a microbi...

W. Skowrońska, Rafał M. Kiełkiewicz, Maja Kirzyc et al. · 0 citations
Open access Sep 2026

Rational Design of Putative Dual-Target Opioid-Dopaminergic Casomorphin–Ranatensin Hybrid Peptides: Computational Modeling and Preliminary Antiproliferative Evaluation

Despite advances in oncology, cancer remains a leading cause of mortality worldwide, and both μ-opioid receptor (MOR) and dopamine D2 receptor (D2R) signaling have been implicated in the regulation of tumor proliferation, survival, and progression, positioning them as attractive targets for multifunctional anticancer s...

Krystian Małek, Adrian Górski, Ł. Szeleszczuk et al. · 0 citations

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